We’re excited to connect with you at ASHG and dive deeper into your research while exploring the exciting world of single cell! Swing by Booth #703 anytime, or join us at our events to spark conversations and share insights. We can’t wait to see you there!
In our CoLab session, Chief Technology Officer Charlie Roco, PhD, will unveil exciting updates to our portfolio of single cell solutions. Highlights include advancements in Evercode Whole Transcriptome, Evercode TCR, Evercode BCR, and Trailmaker, all designed to make single cell more accessible and powerful than ever.
In this session, Elisabeth Rebboah, PhD, from the Mortazavi Lab at UC Irvine, discusses her recent work on the impact of genetic diversity on cell type- and state-specific gene expression in mice.
Through an extensive study of various mouse strains and tissue types, significant diversity in gene expression profiles was uncovered. Single Cell Sequencing analysis of millions of cells revealed that different tissues exhibit varying levels of transcriptional variation due to strain differences, with specific impacts on cell types (e.g., neurons show less variation compared to glial cells and hepatocytes). Rebboah’s findings indicate that genetic diversity correlates with transcriptional variation, with wild-derived strains exhibiting the most differential expression. Additionally, while most cell types show significant variation in wild strains, at least one cell state specific to a common lab strain was identified, which is linked to a known phenotype: activated muscle stem cells in A/J mice, predisposed to muscular dystrophy.
Join Parse Biosciences’ unforgettable third annual Single Cell-ebration! Enjoy an evening of drinks, delicious food, and engaging entertainment, all while connecting with fellow scientists in a cell-ebratory atmosphere. The event will be held just a short 5-minute walk from the Denver Convention Center at the Studio Loft, 980 14th Street, Denver, 80202. The Parse team can’t wait to cell-ebrate with you!
Stop by to chat with our staff about the Evercode technology, join our flash talks at our in-booth theatre, and pick up some of the coolest swag at the conference!